human PTDSS1 shRNA silencing Adenovirus

Name
Ad-h-PTDSS1-shRNA

Cat No
shADV-220227

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PTDSS1.

shADV-220227

Ad-h-PTDSS1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PTDSS1 (phosphatidylserine synthase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

LMHD; PSS1; PSSA

Description (Vector)

Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS1, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 (PubMed 11084049)).(supplied by OMIM, May 2009)

Gene ID

9791

Gene Name (Vector)

phosphatidylserine synthase 1

Gene Symbol

PTDSS1

HGNC ID

HGNC:9587

ORF Size (aa)

984

ORF Size (bp)

984 bp

RefSeq ID

NM_014754

RefSeq Synonyms

NM_014754, NM_001290225, BC004390, BC004192, BC002376,

Species

human

UniGene ID

Hs.292579

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.