human PRRG1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PRRG1.
shADV-220000
Ad-h-PRRG1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PRRG1 (proline rich and Gla domain 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PRGP1
Description (Vector)
PRRG1 encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. PRRG1 is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene.
Gene ID
5638
Gene Name (Vector)
proline rich and Gla domain 1
Gene Symbol
PRRG1
HGNC ID
HGNC:9469
ORF Size (aa)
657
RefSeq ID
NM_000950
RefSeq Synonyms
NM_001173490, NM_001173489, NM_001173486, NM_001142395, NM_000950, BC060833,
Species
human
UniGene ID
Hs.190341
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.