human PRKD3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PRKD3.
shADV-219874
Ad-h-PRKD3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PRKD3 (protein kinase D3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EPK2; nPKC-NU; PKC-NU; PKD3; PRKCN
Description (Vector)
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.
Gene ID
23683
Gene Name (Vector)
protein kinase D3
Gene Symbol
PRKD3
HGNC ID
HGNC:9408
ORF Size (aa)
1836
ORF Size (bp)
1836 bp
RefSeq ID
NM_005813
RefSeq Synonyms
NM_005813, BC030706,
Species
human
UniGene ID
Hs.716034
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.