human PRKACA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PRKACA.
shADV-219840
Ad-h-PRKACA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PRKACA (protein kinase cAMP-activated catalytic subunit alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PKACA; PPNAD4
Description (Vector)
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Gene ID
5566
Gene Name (Vector)
protein kinase cAMP-activated catalytic subunit alpha
Gene Symbol
PRKACA
HGNC ID
HGNC:9380
ORF Size (aa)
1056
ORF Size (bp)
1056 bp
RefSeq ID
NM_002730
RefSeq Synonyms
NM_207518, NM_002730, NM_001304349, BC108259, BC039846,
Species
human
UniGene ID
Hs.631630
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.