human PRDX1 shRNA silencing Adenovirus

Name
Ad-h-PRDX1-shRNA

Cat No
shADV-219767

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PRDX1.

shADV-219767

Ad-h-PRDX1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PRDX1 (peroxiredoxin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

MSP23; NKEF-A; NKEFA; PAG; PAGA; PAGB; PRX1; PRXI; TDPX2

Description (Vector)

PRDX1 encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene.

Gene ID

5052

Gene Name (Vector)

peroxiredoxin 1

Gene Symbol

PRDX1

HGNC ID

HGNC:9352

ORF Size (aa)

600

RefSeq ID

NM_002574

RefSeq Synonyms

NM_181697, NM_181696, NM_002574, NM_001202431, BC021683, BC007063,

Species

human

UniGene ID

Hs.180909

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.