human PPP2R1B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PPP2R1B.
shADV-219650
Ad-h-PPP2R1B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PPP2R1B (protein phosphatase 2 scaffold subunit Abeta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PP2A-Abeta; PR65B
Description (Vector)
PPP2R1B encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. PPP2R1B encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
Gene ID
5519
Gene Name (Vector)
protein phosphatase 2 scaffold subunit Abeta
Gene Symbol
PPP2R1B
HGNC ID
HGNC:9303
ORF Size (aa)
2004
ORF Size (bp)
2004 bp
RefSeq ID
NM_002716
RefSeq Synonyms
NM_181700, NM_181699, NM_002716, NM_001177563, NM_001177562, BC027596,
Species
human
UniGene ID
Hs.584790
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.