human PPP1R15B shRNA silencing Adenovirus

Name 
Ad-h-PPP1R15B-shRNA
Cat No 
shADV-219621
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PPP1R15B.

shADV-219621
Ad-h-PPP1R15B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PPP1R15B (protein phosphatase 1 regulatory subunit 15B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CREP; MSSGM2
Description (Vector)
PPP1R15B promotes dephosphorylation of the transcription initiation factor EIF2-alpha (EIF2S1; MIM 603907) through recruitment of protein phosphatase-1 (PP1) catalytic subunits (see MIM 176875) (Harding et al., 2009 (PubMed 19181853)).(supplied by OMIM, Feb 2010)
Gene ID
84919
Gene Name (Vector)
protein phosphatase 1 regulatory subunit 15B
Gene Symbol
PPP1R15B
HGNC ID
HGNC:14951
ORF Size (aa)
2142
ORF Size (bp)
2142 bp
RefSeq ID
NM_032833
RefSeq Synonyms
NM_032833, BC065280,
Species
human
UniGene ID
Hs.304376

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.