human PPFIA2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PPFIA2.
shADV-219526
Ad-h-PPFIA2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PPFIA2 (PTPRF interacting protein alpha 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
PPFIA2 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein is most closely related to PPFIA1, a liprin family member known to interact with the protein phosphatase LAR. The expression of this gene is found to be downregulated by androgens in a prostate cancer cell line. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
8499
Gene Name (Vector)
PTPRF interacting protein alpha 2
Gene Symbol
PPFIA2
HGNC ID
HGNC:9246
ORF Size (aa)
3756
ORF Size (bp)
3756 bp
RefSeq ID
NM_003625
RefSeq Synonyms
NM_003625, NM_001282536, NM_001220480, NM_001220479, NM_001220478, NM_001220477, NM_001220476, NM_001220475, NM_001220474, NM_001220473, BC143485, BC104912,
Species
human
UniGene ID
Hs.506216
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.