human POU6F2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human POU6F2.
shADV-219490
Ad-h-POU6F2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human POU6F2 (POU class 6 homeobox 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RPF-1; WT5; WTSL
Description (Vector)
POU6F2 encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. POU6F2 is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
11281
Gene Name (Vector)
POU class 6 homeobox 2
Gene Symbol
POU6F2
HGNC ID
HGNC:21694
ORF Size (aa)
2049
ORF Size (bp)
2049 bp
RefSeq ID
NM_007252
RefSeq Synonyms
NM_007252, NM_001166018, BC152915,
Species
human
UniGene ID
Hs.137106
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.