human POU2F3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human POU2F3.
shADV-219475
Ad-h-POU2F3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human POU2F3 (POU class 2 homeobox 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Epoc-1; OCT-11; OCT11; OTF-11; PLA-1; PLA1; Skn-1a
Description (Vector)
POU2F3 encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
25833
Gene Name (Vector)
POU class 2 homeobox 3
Gene Symbol
POU2F3
HGNC ID
HGNC:19864
ORF Size (aa)
1311
ORF Size (bp)
1311 bp
RefSeq ID
NM_014352
RefSeq Synonyms
NM_014352, NM_001244682, BC101649,
Species
human
UniGene ID
Hs.227115
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.