human PON3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PON3.
shADV-219445
Ad-h-PON3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PON3 (paraoxonase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
PON3 is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized.
Gene ID
5446
Gene Name (Vector)
paraoxonase 3
Gene Symbol
PON3
HGNC ID
HGNC:9206
ORF Size (aa)
1065
ORF Size (bp)
1065 bp
RefSeq ID
NM_000940
RefSeq Synonyms
NM_000940, BC070374,
Species
human
UniGene ID
Hs.440967
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.