human POLG2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human POLG2.
shADV-219366
Ad-h-POLG2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human POLG2 (DNA polymerase gamma 2, accessory subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HP55; MTPOLB; PEOA4; POLB; POLG-BETA; POLGB
Description (Vector)
POLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
Gene ID
11232
Gene Name (Vector)
DNA polymerase gamma 2, accessory subunit
Gene Symbol
POLG2
HGNC ID
HGNC:9180
ORF Size (aa)
1458
ORF Size (bp)
1458 bp
RefSeq ID
NM_007215
RefSeq Synonyms
NM_007215, BC009194,
Species
human
UniGene ID
Hs.437009
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.