human POLE4 shRNA silencing Adenovirus

Name 
Ad-h-POLE4-shRNA
Cat No 
shADV-219363
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human POLE4.

shADV-219363
Ad-h-POLE4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human POLE4 (DNA polymerase epsilon 4, accessory subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
p12; YHHQ1
Description (Vector)
POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.(supplied by OMIM, Apr 2004)
Gene ID
56655
Gene Name (Vector)
DNA polymerase epsilon 4, accessory subunit
Gene Symbol
POLE4
HGNC ID
HGNC:18755
ORF Size (aa)
354
RefSeq ID
NM_019896
RefSeq Synonyms
NM_019896, BC031331,
Species
human
UniGene ID
Hs.469060

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.