human POLDIP3 shRNA silencing Adenovirus

Name 
Ad-h-POLDIP3-shRNA
Cat No 
shADV-219355
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human POLDIP3.

shADV-219355
Ad-h-POLDIP3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human POLDIP3 (DNA polymerase delta interacting protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
46 kDa DNA polymerase delta interaction protein; p46; PDIP3; PDIP46; polymerase (DNA) delta interacting protein 3; polymerase (DNA-directed), delta interacting protein 3; polymerase delta-interacting protein 3; RNA-binding protein P46; S6K1 Aly/REF-like target; SKAR
Description (eCommerce)
Polymerase delta-interacting protein 3 (POLDIP3) interacts with the DNA polymerase delta p50 subunit. POLDIP3 is a specific target of S6 kinase 1 and regulates cell growth [taken from NCBI Entrez Gene (Gene ID: 84271)].
Description (Vector)
POLDIP3 encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified.
Gene ID
84271
Gene Name (eCommerce)
DNA polymerase delta interacting protein 3
Gene Name (Vector)
DNA polymerase delta interacting protein 3
Gene Symbol
POLDIP3
HGNC ID
HGNC:23782
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1266
ORF Size (bp)
1266 bp
Protein Name (eCommerce)
Polymerase delta-interacting protein 3
RefSeq ID
NM_032311
RefSeq Synonyms
NM_178136, NM_032311, NM_001278657, BC095411, BC056912, BC049840, BC019643,
Research Areas
mRNA transport,mTOR Signaling,RNA Binding,RNA Transport,Signal Transduction,Translational Control
Research Areas (Faceted)
cell_biology,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
Polymerase delta-interacting protein 3 (POLDIP3) interacts with the DNA polymerase delta p50 subunit. POLDIP3 is a specific target of S6 kinase 1 and regulates cell growth [taken from NCBI Entrez Gene (Gene ID: 84271)].
UniGene ID
Hs.505802
UniProt ID (eCommerce)
Q9BY77

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.