human PODXL shRNA silencing Adenovirus

Name 
Ad-h-PODXL-shRNA
Cat No 
shADV-219332
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PODXL.

shADV-219332
Ad-h-PODXL-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PODXL (podocalyxin like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Gp200; PC; PCLP; PCLP-1
Description (Vector)
PODXL encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
Gene ID
5420
Gene Name (Vector)
podocalyxin like
Gene Symbol
PODXL
HGNC ID
HGNC:9171
ORF Size (aa)
1683
ORF Size (bp)
1683 bp
RefSeq ID
NM_005397
RefSeq Synonyms
NM_005397, NM_001018111, BC143318, BC112035, BC093730,
Species
human
UniGene ID
Hs.690098

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.