human PLK1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PLK1.
shADV-219210
Ad-h-PLK1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PLK1 (polo like kinase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
cell cycle regulated protein kinase; PLK; PLK-1; polo (Drosophia)-like kinase; Polo-like kinase 1; serine/threonine-protein kinase 13; serine/threonine-protein kinase PLK1; STPK13
Description (eCommerce)
Polo-like kinase 1 (PLK1) activity is central to the progression through mitosis. PLK1 plays an essential role in spindle formation and chromosome segregation. Recent studies suggest that PLK1 is specifically involved in anaphase spindle elongation, Rho localization to the contractile ring and cytokinesis.
Gene ID
5347
Gene Name (eCommerce)
polo like kinase 1
Gene Name (Vector)
polo like kinase 1
Gene Symbol
PLK1
HGNC ID
HGNC:9077
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1812
ORF Size (bp)
1812 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase PLK1
RefSeq ID
NM_005030
RefSeq Synonyms
NM_005030, BC014846, BC003002, BC002369,
Research Areas
Apoptosis,Breast Cancer,Cancer,Cell Cycle,Cell Division,Cytoskeleton,DNA Damage/Repair,EPO Signaling,FoxO Signaling,Golgi Apparatus,Immunology,Interleukin Signaling,JAK-STAT Signaling,Kinase/Phosphatase,Meiosis,PLK1 Signaling,Prostate Cancer,Signal Transduction,TNF Signaling,Toll-like Receptor Signaling,VEGF Signaling
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,developmental_biology,genetics,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
Polo-like kinase 1 (PLK1) activity is central to the progression through mitosis. PLK1 plays an essential role in spindle formation and chromosome segregation. Recent studies suggest that PLK1 is specifically involved in anaphase spindle elongation, Rho localization to the contractile ring and cytokinesis.
UniGene ID
Hs.592049
UniProt ID (eCommerce)
P53350
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.