human PISD shRNA silencing Adenovirus

Name
Ad-h-PISD-shRNA

Cat No
shADV-218990

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human PISD.

shADV-218990

Ad-h-PISD-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PISD (phosphatidylserine decarboxylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

DJ858B16; dJ858B16.2; PSD; PSDC; PSSC

Description (Vector)

Phosphatidylserine decarboxylases (PSDs; EC 4.1.1.65) catalyze the formation of phosphatidylethanolamine (PE) by decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits (Schuiki and Daum, 2009 (PubMed 19165886)).(supplied by OMIM, Jul 2010)

Gene ID

23761

Gene Name (Vector)

phosphatidylserine decarboxylase

Gene Symbol

PISD

HGNC ID

HGNC:8999

ORF Size (aa)

1128

ORF Size (bp)

1128 bp

RefSeq ID

NM_014338

RefSeq Synonyms

NM_178022, NM_014338, NM_001326421, NM_001326420, NM_001326419, NM_001326418, NM_001326417, NM_001326416, NM_001326415, NM_001326414, NM_001326413, NM_001326412, NM_001326411, BC001482,

Species

human

UniGene ID

Hs.420559

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.