human PIK3CB shRNA silencing Adenovirus

Name 
Ad-h-PIK3CB-shRNA
Cat No 
shADV-218947
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human PIK3CB.

shADV-218947
Ad-h-PIK3CB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
P110BETA; PI3K; PI3KBETA; PIK3C1
Description (Vector)
PIK3CB encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.
Gene ID
5291
Gene Name (Vector)
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Gene Symbol
PIK3CB
HGNC ID
HGNC:8976
ORF Size (aa)
3213
ORF Size (bp)
3213 bp
RefSeq ID
NM_006219
RefSeq Synonyms
NM_006219, NM_001256045, BC114432,
Species
human
UniGene ID
Hs.239818

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.