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human PHOX2B shRNA silencing Adenovirus

Name 
Ad-h-PHOX2B-shRNA
Cat No 
shADV-218856
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PHOX2B.

shADV-218856
Ad-h-PHOX2B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PHOX2B (paired like homeobox 2b). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
NBLST2; NBPhox; PMX2B
Description (Vector)
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element.
Gene ID
8929
Gene Name (Vector)
paired like homeobox 2b
Gene Symbol
PHOX2B
HGNC ID
HGNC:9143
ORF Size (aa)
945
RefSeq ID
NM_003924
RefSeq Synonyms
NM_003924, BC017199,
Species
human
UniGene ID
Hs.87202

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.