human PIGR shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PIGR.
shAAV-218920
AAV-h-PIGR-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PIGR (polymeric immunoglobulin receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
PIGR is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.
Gene ID
5284
Gene Name (Vector)
polymeric immunoglobulin receptor
Gene Symbol
PIGR
HGNC ID
HGNC:8968
ORF Size (aa)
2295
ORF Size (bp)
2295 bp
RefSeq ID
NM_002644
RefSeq Synonyms
NM_002644, BC110495, BC110494,
Species
human
UniGene ID
Hs.497589
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.