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human PEPD shRNA silencing Adenovirus

Name 
Ad-h-PEPD-shRNA
Cat No 
shADV-218618
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PEPD.

shADV-218618
Ad-h-PEPD-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PEPD (peptidase D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
aminoacyl-L-proline hydrolase; imidodipeptidase; Peptidase D; PROLIDASE; proline dipeptidase; testicular tissue protein Li 138; xaa-Pro dipeptidase; X-Pro dipeptidase
Description (eCommerce)
Peptidase D (PEPD) is a member of the peptidase family. PEPD forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen [taken from NCBI Entrez Gene (Gene ID: 5184)].
Description (Vector)
PEPD encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
5184
Gene Name (eCommerce)
peptidase D
Gene Name (Vector)
peptidase D
Gene Symbol
PEPD
HGNC ID
HGNC:8840
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1482
ORF Size (bp)
1482 bp
Protein Name (eCommerce)
Xaa-Pro dipeptidase
RefSeq ID
NM_000285
RefSeq Synonyms
NM_001166057, NM_001166056, NM_000285, BC028295, BC015027, BC004305,
Research Areas
Cell Biology,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Peptidase D (PEPD) is a member of the peptidase family. PEPD forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen [taken from NCBI Entrez Gene (Gene ID: 5184)].
UniGene ID
Hs.36473
UniProt ID (eCommerce)
P12955

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.