human PAM shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PAM.
shADV-218168
Ad-h-PAM-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PAM (peptidylglycine alpha-amidating monooxygenase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PAL; PHM
Description (Vector)
PAM encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.
Gene ID
5066
Gene Name (Vector)
peptidylglycine alpha-amidating monooxygenase
Gene Symbol
PAM
HGNC ID
HGNC:8596
ORF Size (aa)
2601
ORF Size (bp)
2601 bp
RefSeq ID
NM_000919
RefSeq Synonyms
NM_138822, NM_138821, NM_138766, NM_001319943, NM_001177306, NM_000919, BC018127,
Species
human
UniGene ID
Hs.369430
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.