human PADI3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PADI3.
shADV-218115
Ad-h-PADI3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PADI3 (peptidyl arginine deiminase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PAD3; PDI3
Description (Vector)
PADI3 encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. PADI3 exists in a cluster with four other paralogous genes.
Gene ID
51702
Gene Name (Vector)
peptidyl arginine deiminase 3
Gene Symbol
PADI3
HGNC ID
HGNC:18337
ORF Size (aa)
1995
ORF Size (bp)
1995 bp
RefSeq ID
NM_016233
RefSeq Synonyms
NM_016233, BC109092, BC109091, BC041592,
Species
human
UniGene ID
Hs.149195
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.