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human PADI3 shRNA silencing AAV

Name 
AAV-h-PADI3-shRNA
Cat No 
shAAV-218115
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PADI3.

shAAV-218115
AAV-h-PADI3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PADI3 (peptidyl arginine deiminase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PAD3; PDI3
Description (Vector)
PADI3 encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. PADI3 exists in a cluster with four other paralogous genes.
Gene ID
51702
Gene Name (Vector)
peptidyl arginine deiminase 3
Gene Symbol
PADI3
HGNC ID
HGNC:18337
ORF Size (aa)
1995
ORF Size (bp)
1995 bp
RefSeq ID
NM_016233
RefSeq Synonyms
NM_016233, BC109092, BC109091, BC041592,
Species
human
UniGene ID
Hs.149195

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.