human P2RX1 shRNA silencing Adenovirus

Name
Ad-h-P2RX1-shRNA

Cat No
shADV-218039

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human P2RX1.

shADV-218039

Ad-h-P2RX1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human P2RX1 (purinergic receptor P2X 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

P2X1

Description (Vector)

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

Gene ID

5023

Gene Name (Vector)

purinergic receptor P2X 1

Gene Symbol

P2RX1

HGNC ID

HGNC:8533

ORF Size (aa)

1200

RefSeq ID

NM_002558

RefSeq Synonyms

NM_002558, BC044657, BC027949,

Species

human

UniGene ID

Hs.41735

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.