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human OSMR shRNA silencing Adenovirus

Name 
Ad-h-OSMR-shRNA
Cat No 
shADV-217965
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human OSMR.

shADV-217965
Ad-h-OSMR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human OSMR (oncostatin M receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
IL-31R-beta; IL-31RB; OSMRB; PLCA1
Description (Vector)
OSMR encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
9180
Gene Name (Vector)
oncostatin M receptor
Gene Symbol
OSMR
HGNC ID
HGNC:8507
ORF Size (aa)
2940
ORF Size (bp)
2940 bp
RefSeq ID
NM_003999
RefSeq Synonyms
NM_003999, NM_001323507, NM_001323506, NM_001323505, NM_001323504, NM_001168355, BC125210, BC125209,
Species
human
UniGene ID
Hs.120658

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.