human OGG1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human OGG1.
shADV-217386
Ad-h-OGG1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human OGG1 (8-oxoguanine DNA glycosylase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HMMH; HOGG1; MUTM; OGH1
Description (Vector)
OGG1 encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
Gene ID
4968
Gene Name (Vector)
8-oxoguanine DNA glycosylase
Gene Symbol
OGG1
HGNC ID
HGNC:8125
ORF Size (aa)
1038
ORF Size (bp)
1038 bp
RefSeq ID
NM_002542
RefSeq Synonyms
NM_016829, NM_016828, NM_016827, NM_016826, NM_016821, NM_016820, NM_016819, NM_002542, BC000657,
Species
human
UniGene ID
Hs.380271
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.