human NT5E shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NT5E

Gene Name

5'-nucleotidase ecto

Gene ID

4907

Gene Synonyms

CALJA; CD73; E5NT; eN; eNT; NT; NT5; NTE

ORF Size

1725 bp

RefSeq#

NM_002526

Gene Description

NT5E is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.153952

HGNC ID

HGNC:8021