human NRN1 shRNA silencing Adenovirus

Name
Ad-h-NRN1-shRNA

Cat No
shADV-217088

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human NRN1.

shADV-217088

Ad-h-NRN1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NRN1 (neuritin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

dJ380B8.2; NRN

Description (Vector)

NRN1 is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. In vitro assays demonstrated that this protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis.

Gene ID

51299

Gene Name (Vector)

neuritin 1

Gene Symbol

NRN1

HGNC ID

HGNC:17972

ORF Size (aa)

429

RefSeq ID

NM_016588

RefSeq Synonyms

NM_016588, NM_001278711, NM_001278710, BC042019, BC002683,

Species

human

UniGene ID

Hs.103291

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.