human NRBF2 shRNA silencing Adenovirus

Name 
Ad-h-NRBF2-shRNA
Cat No 
shADV-217067
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NRBF2.

shADV-217067
Ad-h-NRBF2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NRBF2 (nuclear receptor binding factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Comodulator of PPAR and RXR; comodulator of PPAR and RXR 1; comodulator of PPAR and RXR 2; COPR; COPR1; COPR2; NRBF-2; nuclear receptor-binding factor 2
Description (eCommerce)
NRBF2 (nuclear receptor binding factor-2) was originally identified in a yeast two-hybrid screen for factors that interact with the peroxisome proliferator-activated receptor alpha (PPARalpha). In a second study, NRBF2 was also identified in a screen of a keratinocyte cDNA library and named COPR (comodulator of PPAR and RXR). In this study, NRBF2 was proposed to function as a modulator of transcriptional activity that functions to decrease rather than completely repress nuclear-receptor mediated gene expression.
Gene ID
29982
Gene Name (eCommerce)
nuclear receptor binding factor 2
Gene Name (Vector)
nuclear receptor binding factor 2
Gene Symbol
NRBF2
HGNC ID
HGNC:19692
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
864
ORF Size (bp)
864 bp
Protein Name (eCommerce)
Nuclear receptor-binding factor 2
RefSeq ID
NM_030759
RefSeq Synonyms
NM_030759, NM_001282405, BC011707,
Research Areas
Gene Expression,Nuclear Receptor Coactivators,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
NRBF2 (nuclear receptor binding factor-2) was originally identified in a yeast two-hybrid screen for factors that interact with the peroxisome proliferator-activated receptor alpha (PPARalpha). In a second study, NRBF2 was also identified in a screen of a keratinocyte cDNA library and named COPR (comodulator of PPAR and RXR). In this study, NRBF2 was proposed to function as a modulator of transcriptional activity that functions to decrease rather than completely repress nuclear-receptor mediated gene expression.
UniGene ID
Hs.449628
UniProt ID (eCommerce)
Q96F24

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.