human NQO1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NQO1.
shADV-217023
Ad-h-NQO1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NQO1 (NAD(P)H quinone dehydrogenase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DHQU; DIA4; DTD; NMOR1; NMORI; QR1
Description (Vector)
NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
1728
Gene Name (Vector)
NAD(P)H quinone dehydrogenase 1
Gene Symbol
NQO1
HGNC ID
HGNC:2874
ORF Size (aa)
825
RefSeq ID
NM_000903
RefSeq Synonyms
NM_001286137, NM_001025434, NM_001025433, NM_000903, BC007659,
Species
human
UniGene ID
Hs.406515
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.