human NPTX2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NPTX2.
shADV-217009
Ad-h-NPTX2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NPTX2 (neuronal pentraxin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NARP; NP-II; NP2
Description (Vector)
NPTX2 encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Gene ID
4885
Gene Name (Vector)
neuronal pentraxin 2
Gene Symbol
NPTX2
HGNC ID
HGNC:7953
ORF Size (aa)
1296
ORF Size (bp)
1296 bp
RefSeq ID
NM_002523
RefSeq Synonyms
NM_002523, BC048275, BC035339, BC034781, BC009924,
Species
human
UniGene ID
Hs.3281
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.