human NOP2 shRNA silencing Adenovirus

Name 
Ad-h-NOP2-shRNA
Cat No 
shADV-216893
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NOP2.

shADV-216893
Ad-h-NOP2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NOP2 (NOP2 nucleolar protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
NOL1; NOL1/NOP2/Sun domain family, member 1; NOP120; NOP2 nucleolar protein homolog; NSUN1; Nucleolar protein 1; nucleolar protein 1, 120kDa; nucleolar protein 2 homolog; p120; probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase; proliferating-cell nucleolar antigen p120; proliferation-associated nucleolar protein p120; putative ribosomal RNA methyltransferase NOP2
Description (eCommerce)
Nucleolar protein 1 (NOL1) is a protein highly expressed in proliferating cells; it is expressed in G1 and peaks during early S phase. It is proposed to play a role in the regulation of the cell cycle, and it may function as a ribosomal RNA methyltransferase.
Gene ID
4839
Gene Name (eCommerce)
NOP2 nucleolar protein
Gene Name (Vector)
NOP2 nucleolar protein
Gene Symbol
NOP2
HGNC ID
HGNC:7867
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2427
ORF Size (bp)
2427 bp
Protein Name (eCommerce)
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase
RefSeq ID
NM_006170
RefSeq Synonyms
NM_006170, NM_001258310, NM_001258309, NM_001258308, NM_001033714, BC128184, BC128183, BC106072, BC082985, BC065257, BC000656,
Research Areas
Methyltransferase,Neurobiology,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,neurobiology,genetics,transcription_translation
Species
human
Target Sentence
Nucleolar protein 1 (NOL1) is a protein highly expressed in proliferating cells; it is expressed in G1 and peaks during early S phase. It is proposed to play a role in the regulation of the cell cycle, and it may function as a ribosomal RNA methyltransferase.
UniGene ID
Hs.534334
UniProt ID (eCommerce)
P46087

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.