human NOP10 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NOP10.
shADV-216883
Ad-h-NOP10-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NOP10 (NOP10 ribonucleoprotein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DKCB1; NOLA3; NOP10P
Description (Vector)
NOP10 is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. NOP10 encodes a protein related to Saccharomyces cerevisiae Nop10p.
Gene ID
55505
Gene Name (Vector)
NOP10 ribonucleoprotein
Gene Symbol
NOP10
HGNC ID
HGNC:14378
ORF Size (aa)
195
RefSeq ID
NM_018648
RefSeq Synonyms
NM_018648, BC063023, BC008886,
Species
human
UniGene ID
Hs.14317
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.