human NIT2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NIT2.
shADV-216736
Ad-h-NIT2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NIT2 (nitrilase family member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
epididymis secretory sperm binding protein Li 8a; HEL-S-8a; Nit protein 2; nitrilase homolog 2; omega-amidase NIT2
Description (eCommerce)
Nitrilase homolog 2 (NIT2) has an omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NQR4].
Gene ID
56954
Gene Name (eCommerce)
nitrilase family member 2
Gene Name (Vector)
nitrilase family member 2
Gene Symbol
NIT2
HGNC ID
HGNC:29878
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
831
ORF Size (bp)
831 bp
Protein Name (eCommerce)
Omega-amidase NIT2
RefSeq ID
NM_020202
RefSeq Synonyms
NM_020202, BC107890, BC020620,
Research Areas
Mitochondrion
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Nitrilase homolog 2 (NIT2) has an omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NQR4].
UniGene ID
Hs.439152
UniProt ID (eCommerce)
Q9NQR4
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.