human NFIB shRNA silencing Adenovirus

Name 
Ad-h-NFIB-shRNA
Cat No 
shADV-216640
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NFIB.

shADV-216640
Ad-h-NFIB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NFIB (nuclear factor I B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CCAAT-box-binding transcription factor; CTF; HMGIC/NFIB; NF1-B; NF-I/B; NFI-B; NFIB2; NFIB3; NFI-RED; nuclear factor 1 B-type; nuclear factor 1/B; Nuclear factor I/B; TGGCA-binding protein
Description (eCommerce)
Nuclear factor I/B (NFIB) recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O00712].
Gene ID
4781
Gene Name (eCommerce)
nuclear factor I B
Gene Name (Vector)
nuclear factor I B
Gene Symbol
NFIB
HGNC ID
HGNC:7785
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1263
ORF Size (bp)
1263 bp
Protein Name (eCommerce)
Nuclear factor 1 B-type
RefSeq ID
NM_005596
RefSeq Synonyms
NM_005596, NM_001282787, NM_001190738, NM_001190737, BC001283,
Research Areas
Axon Guidance,DNA Replication,Gene Expression,Neurobiology,Neurodevelopment,RNA Binding,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,developmental_biology,genetics,neurobiology,transcription_translation
Species
human
Target Sentence
Nuclear factor I/B (NFIB) recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O00712].
UniGene ID
Hs.644095
UniProt ID (eCommerce)
O00712

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.