human NCOR1 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-216429
Availability:
3-5 weeks
Name:
Ad-h-NCOR1-shRNA
This is an Adenovirus expressing shRNA for silencing of Human NCOR1.
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Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- NCOR1
- Gene Name
- nuclear receptor corepressor 1
- Gene ID
- 9611
- Gene Synonyms
- hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1
- ORF Size
- 7014 bp
- RefSeq#
- NM_006311
- Gene Description
- NCOR1 encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. NCOR1 is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.
- UniGene ID
- Hs.462323
- HGNC ID
- HGNC:7672
Related Products
Product | Cat No. |
---|---|
Ad-h-NCOR1 | ADV-216428 |
Ad-h-NCOR1 | ADV-216429 |
Ad-m-NCOR1 | ADV-265526 |
AAV-h-NCOR1-shRNA | shAAV-216429 |
AAV-m-NCOR1-shRNA | shAAV-265526 |
Ad-m-NCOR1-shRNA | shADV-265526 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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