human NCAPG2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NCAPG2.
shADV-216387
Ad-h-NCAPG2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NCAPG2 (non-SMC condensin II complex subunit G2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAPG2; CAP-G2; chromosome-associated protein G2; condensin-2 complex subunit G2; hCAP-G2; leucine zipper protein 5; LUZP5; more than blood homolog; MTB; Non-SMC condensin II complex subunit G2
Description (eCommerce)
CAP-G2 is a subunit of the heteropentameric condensin II complex. Condensin participates in the condensation of chromosomes during cell division by facilitating positive DNA supercoiling and knotting by topoisomerase I and II and proper segregation of sister chromatids. CAP-G2 is a non-SMC regulatory subunit of the condensin complex.
Description (Vector)
Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPG2 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 (PubMed 14532007)).(supplied by OMIM, Mar 2008)
Gene ID
54892
Gene Name (eCommerce)
non-SMC condensin II complex subunit G2
Gene Name (Vector)
non-SMC condensin II complex subunit G2
Gene Symbol
NCAPG2
HGNC ID
HGNC:21904
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2808
ORF Size (bp)
2808 bp
Protein Name (eCommerce)
Condensin-2 complex subunit G2
RefSeq ID
NM_017760
RefSeq Synonyms
NM_017760, NM_001281933, NM_001281932, BC043404, BC020560,
Research Areas
Cell Cycle,Cell Division
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
CAP-G2 is a subunit of the heteropentameric condensin II complex. Condensin participates in the condensation of chromosomes during cell division by facilitating positive DNA supercoiling and knotting by topoisomerase I and II and proper segregation of sister chromatids. CAP-G2 is a non-SMC regulatory subunit of the condensin complex.
UniGene ID
Hs.18616
UniProt ID (eCommerce)
Q86XI2
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.