human NBL1 shRNA silencing Adenovirus

Name 
Ad-h-NBL1-shRNA
Cat No 
shADV-216363
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human NBL1.

shADV-216363
Ad-h-NBL1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NBL1 (neuroblastoma 1, DAN family BMP antagonist). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
D1S1733E; DAN; DAND1; NB; NO3
Description (Vector)
NBL1 product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream chromosome 1 open reading frame 151 locus (GeneID 440574) have been observed.
Gene ID
4681
Gene Name (Vector)
neuroblastoma 1, DAN family BMP antagonist
Gene Symbol
NBL1
HGNC ID
HGNC:7650
ORF Size (aa)
543
RefSeq ID
NM_005380
RefSeq Synonyms
NM_182744, NM_005380, NM_001278166, NM_001278165, NM_001278164, NM_001204086, NM_001204085, NM_001204084, BC012037,
Species
human
UniGene ID
Hs.654502

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.