human MRPL1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MRPL1.
shADV-215772
Ad-h-MRPL1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MRPL1 (mitochondrial ribosomal protein L1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BM022; L1MT; MRP-L1
Description (Vector)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family.
Gene ID
65008
Gene Name (Vector)
mitochondrial ribosomal protein L1
Gene Symbol
MRPL1
HGNC ID
HGNC:14275
ORF Size (aa)
912
ORF Size (bp)
912 bp
RefSeq ID
NM_020236
RefSeq Synonyms
NM_020236, BC032595, BC015109, BC014356,
Species
human
UniGene ID
Hs.532019
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.