human MEF2D shRNA silencing Adenovirus

Name 
Ad-h-MEF2D-shRNA
Cat No 
shADV-215275
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human MEF2D.

shADV-215275
Ad-h-MEF2D-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MEF2D (myocyte enhancer factor 2D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MADS box transcription enhancer factor 2, polypeptide D; myocyte-specific enhancer factor 2D
Description (eCommerce)
Myocyte-specific enhancer factor 2D (MEF2D) is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth-factor and stress-induced genes. MEF2D mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14814].
Gene ID
4209
Gene Name (eCommerce)
myocyte enhancer factor 2D
Gene Name (Vector)
myocyte enhancer factor 2D
Gene Symbol
MEF2D
HGNC ID
HGNC:6997
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1545
ORF Size (bp)
1545 bp
Protein Name (eCommerce)
Myocyte-specific enhancer factor 2D
RefSeq ID
NM_005920
RefSeq Synonyms
NM_005920, NM_001271629, BC054520, BC040949,
Research Areas
Apoptosis,B-cell Receptor Signaling,Cardiac Development,Cardiology,Cardiovascular,Immunology,MAPK Signaling,Metabolism/Metabolic Process,Neurobiology,Neurodevelopment,Neurogenesis,NFAT Signaling,RNA Binding,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cardiovascular,cell_biology,developmental_biology,immunology,metabolism,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Myocyte-specific enhancer factor 2D (MEF2D) is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth-factor and stress-induced genes. MEF2D mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14814].
UniGene ID
Hs.314327
UniProt ID (eCommerce)
Q14814

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.