human MCOLN1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MCOLN1.
shADV-215197
Ad-h-MCOLN1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MCOLN1 (mucolipin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MG-2; ML4; MLIV; MST080; MSTP080; TRP-ML1; TRPM-L1; TRPML1
Description (Vector)
MCOLN1 encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV.
Gene ID
57192
Gene Name (Vector)
mucolipin 1
Gene Symbol
MCOLN1
HGNC ID
HGNC:13356
ORF Size (aa)
1743
ORF Size (bp)
1743 bp
RefSeq ID
NM_020533
RefSeq Synonyms
NM_020533, BC005149,
Species
human
UniGene ID
Hs.631858
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.