human MCCC1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MCCC1.
shADV-215157
Ad-h-MCCC1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MCCC1 (methylcrotonoyl-CoA carboxylase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MCC-B; MCCA
Description (Vector)
MCCC1 encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.
Gene ID
56922
Gene Name (Vector)
methylcrotonoyl-CoA carboxylase 1
Gene Symbol
MCCC1
HGNC ID
HGNC:6936
ORF Size (aa)
2178
ORF Size (bp)
2178 bp
RefSeq ID
NM_020166
RefSeq Synonyms
NM_020166, NM_001293273, BC004214, BC004187,
Species
human
UniGene ID
Hs.47649
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.