human MBNL2 shRNA silencing Adenovirus

Name
Ad-h-MBNL2-shRNA

Cat No
shADV-215107

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human MBNL2.

shADV-215107

Ad-h-MBNL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MBNL2 (muscleblind like splicing regulator 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

MBLL; MBLL39; PRO2032

Description (Vector)

MBNL2 is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. MBNL2 encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.

Gene ID

10150

Gene Name (Vector)

muscleblind like splicing regulator 2

Gene Symbol

MBNL2

HGNC ID

HGNC:16746

ORF Size (aa)

1086

ORF Size (bp)

1086 bp

RefSeq ID

NM_207304

RefSeq Synonyms

NM_207304, NM_144778, NM_001306070, BC104040, BC104039, BC104038,

Species

human

UniGene ID

Hs.657347

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.