human MAL shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MAL.
shADV-214859
Ad-h-MAL-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MAL (mal, T-cell differentiation protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
MAL is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.
Gene ID
4118
Gene Name (Vector)
mal, T-cell differentiation protein
Gene Symbol
MAL
HGNC ID
HGNC:6817
ORF Size (aa)
462
RefSeq ID
NM_002371
RefSeq Synonyms
NM_022440, NM_022439, NM_022438, NM_002371, BC003006, BC000458,
Species
human
UniGene ID
Hs.80395
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.