human LTA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human LTA.
shADV-214657
Ad-h-LTA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human LTA (lymphotoxin alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LT; TNFB; TNFSF1; TNLG1E
Description (Vector)
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.
Gene ID
4049
Gene Name (Vector)
lymphotoxin alpha
Gene Symbol
LTA
HGNC ID
HGNC:6709
ORF Size (aa)
618
RefSeq ID
NM_000595
RefSeq Synonyms
NM_001159740, NM_000595, BC034729,
Species
human
UniGene ID
Hs.36
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.