human LSM14A shRNA silencing Adenovirus

Name 
Ad-h-LSM14A-shRNA
Cat No 
shADV-214635
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human LSM14A.

shADV-214635
Ad-h-LSM14A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human LSM14A (LSM14A, mRNA processing body assembly factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
alphaSNBP; C19orf13; FAM61A; family with sequence similarity 61, member A; hRAP55; hRAP55A; LSM14 homolog A; LSM14A, SCD6 homolog A; Protein FAM61A; protein LSM14 homolog A; protein SCD6 homolog; putative alpha-synuclein-binding protein; RAP55; RAP55A; RNA-associated protein 55; RNA-associated protein 55A
Description (eCommerce)
LSM14A encodes Protein LSM14 homolog A, a Sm-like protein. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing [taken from NCBI Entrez Gene (Gene ID: 26065)].U6 snRNA-associated Sm-like protein LSm7 is encoded by the gene LSM7. Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing [taken from NCBI Entrez Gene (Gene ID: 51690)].
Description (Vector)
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.(supplied by OMIM, Mar 2008)
Gene ID
26065
Gene Name (eCommerce)
LSM14A, mRNA processing body assembly factor
Gene Name (Vector)
LSM14A, mRNA processing body assembly factor
Gene Symbol
LSM14A
HGNC ID
HGNC:24489
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1392
ORF Size (bp)
1392 bp
Protein Name (eCommerce)
Protein LSM14 homolog A
RefSeq ID
NM_015578
RefSeq Synonyms
NM_015578, NM_001114093, BC016842,
Research Areas
RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
LSM14A encodes Protein LSM14 homolog A, a Sm-like protein. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing [taken from NCBI Entrez Gene (Gene ID: 26065)].U6 snRNA-associated Sm-like protein LSm7 is encoded by the gene LSM7. Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing [taken from NCBI Entrez Gene (Gene ID: 51690)].
UniGene ID
Hs.718430
UniProt ID (eCommerce)
Q8ND56

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.