human LPAR1 shRNA silencing Adenovirus

Name 
Ad-h-LPAR1-shRNA
Cat No 
shADV-214443
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human LPAR1.

shADV-214443
Ad-h-LPAR1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human LPAR1 (lysophosphatidic acid receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
edg-2; EDG2; Gpcr26; GPR26; LPA1; Mrec1.3; rec.1.3; vzg-1; VZG1
Description (Vector)
The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene
Gene ID
1902
Gene Name (Vector)
lysophosphatidic acid receptor 1
Gene Symbol
LPAR1
HGNC ID
HGNC:3166
ORF Size (aa)
1095
RefSeq ID
NM_057159
RefSeq Synonyms
NM_057159, NM_001401, BC073167, BC036034, BC030615,
Species
human
UniGene ID
Hs.126667

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.