human LOC25845 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human EXOC3.
shADV-214221
Ad-h-LOC25845-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human EXOC3 (exocyst complex component 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SEC6; SEC6L1; Sec6p
Description (Vector)
EXOC3 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Gene ID
11336
Gene Name (Vector)
exocyst complex component 3
Gene Symbol
EXOC3
HGNC ID
HGNC:30378
ORF Size (aa)
2238
ORF Size (bp)
2238 bp
RefSeq ID
NM_007277
RefSeq Synonyms
NM_007277, BC064569,
Species
human
UniGene ID
Hs.481464
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.