human SDHC shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SDHC.
shADV-214170
Ad-h-SDHC-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SDHC (succinate dehydrogenase complex subunit C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CYB560; CYBL; PGL3; QPS1; SDH3
Description (Vector)
SDHC encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
6391
Gene Name (Vector)
succinate dehydrogenase complex subunit C
Gene Symbol
SDHC
HGNC ID
HGNC:10682
ORF Size (aa)
510
RefSeq ID
NM_003001
RefSeq Synonyms
NM_003001, NM_001278172, NM_001035513, NM_001035512, NM_001035511, BC066329, BC033626, BC020808,
Species
human
UniGene ID
Hs.444472
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.